While there have been a number of less exciting reports on UWO’s drug testing research in the past, an article posted a little while ago outlines a few breakthroughs of much higher value. You can read the full article here, but I have also smoked out the more important details, and tightly rolled them into a comprehensive list… Accompanied by hot girls smoking weed, because that’s how my brain works.
1 – Team Green
Steven Laviolette and the research team from Western’s Schullich School of Medicine and Dentistry have been analyzing the 70 chemical components that make up marijuana, in an effort to isolate the ones that cause paranoia and other emotional imbalances.
2 – Dopest Dopamine
In a series of tests on rats, the research team has been studying how chemical compounds found in weed interact with cannabinoid receptors in the prefrontal cortex of the brain and link to the dopamine system, which factors into our emotions.
For you non-science types, this means that they got a bunch of rats really fucking high, and watched what happened to their brains, while they got hella blitzed on that good-good.
3 – Mixed Results
The researchers expected that the rats would experience a degradation of emotional processing, as a side effect of weed exposure, because the dopamine system would become impaired, and the result of these trials were consistent with their postulations. What they did not expect to find, was that this relation did not remain consistent as the dosage increased.
It turns out that at extremely high doses of cannabinoid exposure, the rats did not simply experience a higher degradation of emotional processes, but a blunting of their emotional responsiveness, and numbness to emotionally salient experiences.
For those of you that are already high (in celebration of this study), this means that when the rats greened, out they stopped getting paranoid, and simply didn’t give a fuck about anything happening around them.
4 – The Next Step
The researchers did not only observe how the rats reacted to having marijuana in their systems, but they also introduced various antipsychotic medications to their systems, in an effort to prevent the paranoia the rats experienced at low doses and the blunting effect experienced at high doses.
5 - Seeing Green
Medical marijuana is becoming a more common treatment for a plethora of ailments, and both Canada and the United States are getting closer and closer to legalizing marijuana at a federal level. With that in mind, you can imagine that there could be a lot of money in developing a pharmaceutical product that would negate some of the stereotypical side effects of the drug, or even patenting a strain of marijuana that did not include the cannabinoid compounds that caused them. Without the alleged “long term negative effects” of marijuana use in play, prohibition lobbyists would have to watch as their arguments went up in smoke.
On a federal level, the government could very well mandate that all medically issued marijuana doses would have to be accompanied by cannabinoid specific antipsychotic medications that stem from this study. As more and more people begin to preemptively invest in marijuana growth and distribution ventures, research like this could lead to the development of other legitimate weed-related revenue streams.
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